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Erectile dysfunction causes men to manufacture PDE-5 enzymes, which hinder erections by destroying cGMP. Tadalafil, an active element in Vidalista 60 and Vidalista 40, assists in muscle relaxation and blood vessel dilation in the reproductive organ. Vidalista 60 mg Tadalafil is a type of medication known as a PDE-5 inhibitor. It inhibits the action of PDE-5 enzymes, preventing cGMP degradation. Blood flow into the male penile increases as cGMP production increases, resulting in an erection.